IPD

The state of the fight: 

African vaccine production advanced on multiple fronts, including the opening of a new manufacturing plant in South Africa.
  The COVAX AMC seeks an additional $5.2 billion this year.
  Merck will supply UNICEF with up to 3 million courses of molnupiravir in the first half of 2022.

AUTHORIZED VACCINES  

The Chilean health ministry released data on the Sinovac jab’s effectiveness in children. In kids ages 6-11, the topline numbers…

Belgium-based biomanufacturing platform company Univercells announced Tuesday that it has signed letters of intent with two Senegal-based organizations to strengthen local vaccine manufacturing capacity. The company will work with the Institute for Health Research, Epidemiological Surveillance and Training to strengthen its R&D capabilities and create bioproduction capacity for routine immunization vaccines, and will also partner with Institut Pasteur de Dakar to rapidly establish local…

The Lancet published results last week from a Médecins Sans Frontières-funded study showing that fractional dosing of any of the four yellow fever vaccines prequalified by WHO produces non-inferior seroconversion compared to a standard dose.

A separate 2018 study demonstrated that a one-fifth dose of Sanofi’s 17D-YFV vaccine protected for 10 years after immunization. The new trials add evidence for the products from Brazil’s Bio-Manguinhos, Senegal’s Institut Pasteur de Dakar and…

WHO’s Strategic Advisory Group of Experts (SAGE) on Immunization has recommended that countries use a dose-sparing yellow fever shot to help alleviate vaccine shortages.

According to a WHO press release last week, SAGE found sufficient evidence to determine that one-fifth fractional dosing of yellow fever vaccine “could be a safe and effective option for mass vaccination campaigns to control urban outbreaks in situations of acute vaccine shortage”.

SAGE chairman Jon Abramson…